Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716433 | 0.93 | ELANE (0.40) | KDM4EALDH1A1ELANEGAALMNA | |
| SCHEMBL11716939 | 0.90 | GSK3B (0.36) | KDM4EALDH1A1ELANEGAAGSK3B | |
| SCHEMBL11711439 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1ELANEGAAGSK3B | |
| SCHEMBL11717020 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1ELANEGAATP53 | |
| SCHEMBL11711347 | 0.84 | TP53 (0.40) | KDM4EALDH1A1ELANEGAATP53 | |
| SCHEMBL11712229 | 0.83 | MAOA (0.41) | KDM4EALDH1A1GAAGSK3BMMP2 | |
| SCHEMBL11715783 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1ELANEGAATP53 | |
| SCHEMBL11715552 | 0.81 | TP53 (0.36) | KDM4EALDH1A1ELANEGAATP53 | |
| SCHEMBL11716760 | 0.79 | GSK3B (0.40) | GSK3BCDK4CCND1USP2 | |
| SCHEMBL11718132 | 0.79 | LMNA (0.41) | KDM4EALDH1A1ELANEGSK3BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |