Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31282172 | 0.86 | KMT2A (0.49) | KMT2ACYP2C9MAPTHTTCYP2C19 | |
| SCHEMBL456749 | 0.79 | HPGD (0.57) | — | |
| SCHEMBL4352816 | 0.78 | HPGD (0.64) | KMT2ACYP2C9MAPTHTTCYP2C19 | |
| SCHEMBL31281981 | 0.78 | KMT2A (0.44) | KMT2ACYP2C9MAPTCYP2C19CYP1A2 | |
| SCHEMBL136440 | 0.77 | HDAC6 (0.43) | KMT2ACYP2C9MAPTHTTCYP1A2 | |
| SCHEMBL692624 | 0.76 | LMNA (0.61) | KMT2ACYP1A2KDM4ESMN1; SMN2LMNA | |
| SCHEMBL770144 | 0.76 | KMT2A (0.60) | KMT2ACYP2C9MAPTCYP1A2ALDH1A1 | |
| SCHEMBL30423828 | 0.76 | GRIA1 (0.60) | KMT2ALMNA | |
| SCHEMBL2153060 | 0.76 | GRIA1 (0.60) | KMT2ACYP2C19CYP1A2MEN1GAA | |
| Ethylene Glycol SCHEMBL9298238 | 0.75 | HPGD (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008221-A | BACTERICIDE, ANTIBIOTIC | RICHARDSON-MERRELL INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-3956288-A | 7-[(2,4-Dioxo-1-pyrimidinyl)acylamino]cephalosporin derivatives | RICHARDSON-MERRELL INC. (US) | 1976-05-11 | — | — | US | disclosed |