Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456749 | 0.81 | HPGD (0.57) | TK1 | |
| SCHEMBL17870803 | 0.80 | UPP1 (0.64) | UPP1 | |
| SCHEMBL23957853 | 0.80 | MAPK1 (0.43) | KMT2AMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL136440 | 0.78 | HDAC6 (0.43) | KMT2AKDM4EMAPTALDH1A1POLB | |
| SCHEMBL11711890 | 0.78 | KMT2A (0.67) | KMT2AKDM4EMAPTALDH1A1POLB | |
| SCHEMBL17870743 | 0.77 | DUT (0.39) | KMT2AKDM4EMAPTALDH1A1POLB | |
| SCHEMBL692624 | 0.77 | LMNA (0.61) | KMT2AKDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL770144 | 0.77 | KMT2A (0.60) | KMT2AKDM4EMAPTALDH1A1POLB | |
| SCHEMBL2153060 | 0.77 | GRIA1 (0.60) | KMT2AALDH1A1CYP1A2GRIA1GRIA2 | |
| SCHEMBL31282172 | 0.77 | KMT2A (0.49) | KMT2AKDM4EMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176815-A | Camptothecin-20-site ester derivative, preparation method thereof, pharmaceutical composition and application thereof | 北京中医药大学 | 2024-12-24 | — | — | CN | disclosed |