Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713977 | 0.89 | METAP2 (0.36) | GSK3BL3MBTL1PTGER4MAPTMEN1 | |
| SCHEMBL11712853 | 0.88 | PTGER4 (0.37) | GSK3BCDK4CCND1GSK3ACDK5 | |
| SCHEMBL11716003 | 0.88 | PTGER4 (0.39) | GSK3BCDK4CCND1GSK3ACDK5 | |
| SCHEMBL11722544 | 0.87 | PTGER4 (0.38) | GSK3BCDK4CCND1GSK3ACDK5 | |
| SCHEMBL11713383 | 0.87 | GSK3B (0.36) | GSK3BCDK4CCND1GSK3ACDK5 | |
| SCHEMBL11715487 | 0.85 | GSK3B (0.36) | GSK3BCDK4CCND1GSK3ACDK5 | |
| SCHEMBL11709013 | 0.80 | ALDH1A1 (0.46) | GSK3BCHEK1MEN1KMT2A | |
| SCHEMBL11712283 | 0.80 | CDK4 (0.40) | GSK3BCDK4CCND1GSK3ACDK5 | |
| SCHEMBL11718278 | 0.79 | ALDH1A1 (0.35) | GSK3BCDK4CCND1L3MBTL1PTGER4 | |
| SCHEMBL11717134 | 0.78 | KDM4E (0.43) | GSK3BCDK4CCND1GSK3ACDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |