Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 1/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718146 | 0.87 | USP2 (0.47) | ALDH1A1USP2TSHRHSD17B10MAOA | |
| SCHEMBL11716003 | 0.85 | PTGER4 (0.39) | GAAGSK3BELANECHEK1MEN1 | |
| SCHEMBL11712853 | 0.83 | PTGER4 (0.37) | ALDH1A1GSK3BHPGDCASP3CCNB2 | |
| SCHEMBL11715487 | 0.82 | GSK3B (0.36) | ALDH1A1GSK3BCCNB2CCNE2CDK1 | |
| SCHEMBL11722544 | 0.82 | PTGER4 (0.38) | ALDH1A1TSHRMAOAMAOBLMNA | |
| SCHEMBL11712283 | 0.82 | CDK4 (0.40) | ALDH1A1TSHRHSD17B10GSK3BELANE | |
| SCHEMBL11713383 | 0.82 | GSK3B (0.36) | ALDH1A1GSK3BCCNB2CDK1CCNB1 | |
| SCHEMBL11717134 | 0.80 | KDM4E (0.43) | ALDH1A1GSK3BSTK10SLKCCNB2 | |
| SCHEMBL11712229 | 0.80 | MAOA (0.41) | ALDH1A1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL11712173 | 0.80 | NCF1 (0.34) | GSK3BCHEK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |