Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.40 |
| ▸ | CCND1 | P24385 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11716003 | 0.85 | PTGER4 (0.39) | CDK4CCND1GSK3BELANECDK5 | |
| SCHEMBL11714135 | 0.84 | CDK4 (0.35) | CDK4CCND1GSK3BCDK5CDK5R1 | |
| SCHEMBL11712853 | 0.83 | PTGER4 (0.37) | CDK4CCND1GSK3BCDK5CDK5R1 | |
| SCHEMBL11717630 | 0.82 | GSK3B (0.38) | CDK4CCND1GSK3BCDK5CDK5R1 | |
| SCHEMBL11715487 | 0.82 | GSK3B (0.36) | CDK4CCND1GSK3BCDK5CDK5R1 | |
| SCHEMBL11709013 | 0.82 | ALDH1A1 (0.46) | GSK3BELANEALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11713383 | 0.82 | GSK3B (0.36) | CDK4CCND1GSK3BCDK5CDK5R1 | |
| SCHEMBL11722544 | 0.82 | PTGER4 (0.38) | CDK4CCND1GSK3BCDK5CDK5R1 | |
| SCHEMBL11717134 | 0.80 | KDM4E (0.43) | CDK4CCND1GSK3BCDK5CDK5R1 | |
| SCHEMBL11712173 | 0.80 | NCF1 (0.34) | CDK4CCND1GSK3BCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |