Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717020 | 0.89 | KDM4E (0.39) | PTGER4CYP1A2CYP2D6GSK3BCDK4 | |
| SCHEMBL11714396 | 0.88 | PTGER4 (0.38) | PTGER4GSK3BCDK4CCND1GAA | |
| SCHEMBL11716003 | 0.87 | PTGER4 (0.39) | PTGER4CYP1A2CYP2D6GSK3BCDK4 | |
| SCHEMBL11712851 | 0.87 | KDR (0.41) | PTGER4CYP1A2GSK3BCDK4CCND1 | |
| SCHEMBL11716329 | 0.87 | LMNA (0.43) | PTGER4CYP1A2CYP2D6HSD17B10ELANE | |
| SCHEMBL11718146 | 0.87 | USP2 (0.47) | GSK3BCDK4CCND1GAAMAPT | |
| SCHEMBL11715694 | 0.87 | CDK4 (0.37) | GSK3BCDK4CCND1GAAMAPT | |
| SCHEMBL11714573 | 0.84 | EGFR (0.45) | CYP1A2CYP2D6MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11716939 | 0.84 | GSK3B (0.36) | CYP1A2GSK3BCDK4CCND1GAA | |
| SCHEMBL11718278 | 0.83 | ALDH1A1 (0.35) | PTGER4GSK3BCDK4CCND1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |