Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11714396 | 0.85 | PTGER4 (0.38) | KDM4EALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL11715694 | 0.84 | CDK4 (0.37) | EGFRPDGFRBFGFR1KDRKDM4E | |
| SCHEMBL11712259 | 0.84 | PTGER4 (0.38) | KDRKDM4ECYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL11712851 | 0.82 | KDR (0.41) | EGFRKDRKDM4ECYP1A2CYP2C9 | |
| SCHEMBL11718278 | 0.81 | ALDH1A1 (0.35) | KDM4EHTTALDH1A1MAPTLMNA | |
| SCHEMBL11718146 | 0.80 | USP2 (0.47) | ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL11711347 | 0.78 | TP53 (0.40) | KDM4EALDH1A1KMT2ALMNAHTR1B | |
| SCHEMBL11715783 | 0.77 | KDM4E (0.37) | KDM4EHTTALDH1A1MAPTLMNA | |
| SCHEMBL11712722 | 0.77 | LMNA (0.41) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11716939 | 0.77 | GSK3B (0.36) | KDRKDM4ECYP1A2LTA4HCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |