Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719736 | 0.90 | KDM4E (0.38) | GSK3BCDK4CCND1MAOAMAOB | |
| SCHEMBL11716760 | 0.88 | GSK3B (0.40) | GSK3BCDK4CCND1KDR | |
| SCHEMBL11716433 | 0.88 | ELANE (0.40) | ELANEKDM4EMAPTGAAHSD17B10 | |
| SCHEMBL11712229 | 0.85 | MAOA (0.41) | GSK3BCDK4CCND1MAOAMAOB | |
| SCHEMBL11712851 | 0.85 | KDR (0.41) | GSK3BCDK4CCND1ELANEKDM4E | |
| SCHEMBL11712259 | 0.84 | PTGER4 (0.38) | GSK3BCDK4CCND1ELANEKDM4E | |
| SCHEMBL11714114 | 0.84 | GSK3B (0.34) | GSK3BCDK4CCND1KDM4EMAPT | |
| SCHEMBL11718146 | 0.82 | USP2 (0.47) | GSK3BCDK4CCND1MAOAMAOB | |
| SCHEMBL11714396 | 0.81 | PTGER4 (0.38) | GSK3BCDK4CCND1KDM4EMAPT | |
| SCHEMBL11718172 | 0.80 | CDK4 (0.36) | GSK3BCDK4CCND1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |