Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | STK10 | O94804 | 1/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709013 | 0.87 | ALDH1A1 (0.46) | USP2ALDH1A1TSHRHSD17B10POLB | |
| SCHEMBL11712259 | 0.87 | PTGER4 (0.38) | ALDH1A1HSD17B10GSK3BCDK4CCND1 | |
| SCHEMBL11714396 | 0.84 | PTGER4 (0.38) | ALDH1A1TSHRHSD17B10LMNAGSK3B | |
| SCHEMBL11712851 | 0.83 | KDR (0.41) | ALDH1A1HSD17B10HPGDGSK3BCDK4 | |
| SCHEMBL11715694 | 0.82 | CDK4 (0.37) | USP2ALDH1A1TSHRHSD17B10GSK3B | |
| SCHEMBL11716939 | 0.82 | GSK3B (0.36) | ALDH1A1TSHRHSD17B10MAOAMAOB | |
| SCHEMBL11714573 | 0.80 | EGFR (0.45) | ALDH1A1POLBLMNAMAPT | |
| SCHEMBL11718278 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TSHRHSD17B10LMNAHPGD | |
| SCHEMBL11717020 | 0.77 | KDM4E (0.39) | ALDH1A1TSHRHSD17B10LMNAGSK3B | |
| SCHEMBL11714114 | 0.77 | GSK3B (0.34) | ALDH1A1TSHRHSD17B10GSK3BCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |