Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465015 | 0.83 | LMNA (0.57) | MTNR1AMTNR1BLMNAKDM4EPOLB | |
| SCHEMBL8501371 | 0.83 | LMNA (0.57) | MTNR1AMTNR1BLMNAKDM4EPOLB | |
| SCHEMBL8502533 | 0.83 | LMNA (0.57) | MTNR1AMTNR1BLMNAKDM4EPOLB | |
| SCHEMBL11721603 | 0.81 | DRD2 (0.46) | MTNR1AMTNR1BLMNAKDM4EPARP1 | |
| SCHEMBL11717346 | 0.78 | ADRB2 (0.37) | MTNR1AMTNR1BLMNAKDM4EPOLB | |
| SCHEMBL24733606 | 0.76 | MTNR1A (0.40) | MTNR1AMTNR1BLMNAKDM4EPOLB | |
| SCHEMBL11594202 | 0.76 | DRD2 (0.52) | KDM4EKMT2ACYP1A2CYP2D6 | |
| SCHEMBL11594200 | 0.76 | DRD2 (0.52) | KDM4EKMT2ACYP1A2CYP2D6 | |
| SCHEMBL11594197 | 0.76 | DRD2 (0.52) | KDM4EKMT2ACYP1A2CYP2D6 | |
| SCHEMBL10205808 | 0.75 | PARP1 (0.47) | MTNR1AMTNR1BLMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041079-A | Bicyclic compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-08-09 | — | — | US | disclosed |