Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.53 |
| ▸ | TUBB | P07437 | 2/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465015 | 1.00 | LMNA (0.57) | LMNAKDM4EPOLBMAPTTUBB1 | |
| SCHEMBL8502533 | 1.00 | LMNA (0.57) | LMNAKDM4EPOLBMAPTTUBB1 | |
| SCHEMBL5262628 | 0.84 | LMNA (0.43) | LMNAKDM4EPOLBMAPTTUBB1 | |
| SCHEMBL11716633 | 0.83 | MTNR1A (0.46) | LMNAKDM4EPOLBMAPTTUBB1 | |
| SCHEMBL11720868 | 0.83 | LMNA (0.71) | LMNAKDM4EPOLBMAPTTUBB1 | |
| SCHEMBL10205808 | 0.78 | PARP1 (0.47) | LMNAKDM4EPOLBMAPTCYP1A2 | |
| SCHEMBL11001128 | 0.77 | MTNR1A (0.66) | MTNR1AMTNR1B | |
| SCHEMBL17304592 | 0.76 | PAX8 (0.53) | LMNAKDM4EPOLBMAPTTUBB1 | |
| Acetic Acid SCHEMBL355654 | 0.76 | ACHE (0.47) | KDM4EMAPTTUBB1TUBB4ATUBB | |
| SCHEMBL559163 | 0.75 | PARP1 (0.47) | KDM4EMAPTCYP1A2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877218-A | PARKINSON'S DISEASE; ANTIEPILEPSY AGENTS; ANTICONVULSANTS | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1999-03-02 | — | — | US | claimed |