Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.41 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712229 | 0.91 | MAOA (0.41) | EGFRSRCROCK2CDK4CCND1 | |
| SCHEMBL11717398 | 0.90 | HPGD (0.41) | ROCK2CDK4CCND1KDM4EALDH1A1 | |
| SCHEMBL11717134 | 0.86 | KDM4E (0.43) | EGFRSRCROCK2CDK4CCND1 | |
| SCHEMBL11720540 | 0.85 | MAOA (0.50) | ROCK2CDK4CCND1CCNE2CCNE1 | |
| SCHEMBL11718192 | 0.81 | MAPT (0.41) | CDK4CCND1CAMK2BCAMK2GCAMK2D | |
| SCHEMBL11717630 | 0.77 | GSK3B (0.38) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL11716003 | 0.77 | PTGER4 (0.39) | CDK4CCND1GAAGSK3BMAPT | |
| SCHEMBL11722544 | 0.76 | PTGER4 (0.38) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL11713383 | 0.76 | GSK3B (0.36) | CDK4CCND1CDK2ALDH1A1GSK3B | |
| SCHEMBL11716939 | 0.76 | GSK3B (0.36) | CDK4CCND1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |