Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 6/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CCND1 | P24385 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718359 | 0.91 | EGFR (0.41) | GSK3BCDK4CCND1KDM4EMAPT | |
| SCHEMBL11717398 | 0.91 | HPGD (0.41) | MAOAMAOBGSK3BCDK4CCND1 | |
| SCHEMBL11718192 | 0.87 | MAPT (0.41) | MAOAMAOBGSK3BCDK4CCND1 | |
| SCHEMBL11720540 | 0.85 | MAOA (0.50) | MAOAMAOBGSK3BCDK4CCND1 | |
| SCHEMBL11716939 | 0.85 | GSK3B (0.36) | MAOAMAOBGSK3BCDK4CCND1 | |
| SCHEMBL11717134 | 0.84 | KDM4E (0.43) | GSK3BCDK4CCND1GSK3ACDK5 | |
| SCHEMBL11719736 | 0.83 | KDM4E (0.38) | MAOAMAOBGSK3BCDK4CCND1 | |
| SCHEMBL11716433 | 0.81 | ELANE (0.40) | KDM4EMAPTKMT2AALDH1A1MMP2 | |
| SCHEMBL11717630 | 0.80 | GSK3B (0.38) | GSK3BCDK4CCND1GSK3ACDK5 | |
| SCHEMBL11716003 | 0.80 | PTGER4 (0.39) | GSK3BCDK4CCND1GSK3ACDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |