Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771288 | 0.79 | MAOA (0.47) | MAOBKDM1AMAOADDB1CRBN | |
| SCHEMBL12188964 | 0.76 | MAOB (0.50) | MAOBKDM1AMAOADDB1CRBN | |
| SCHEMBL13888944 | 0.76 | MAOB (0.50) | MAOBKDM1AMAOADDB1CRBN | |
| SCHEMBL26933019 | 0.75 | MAOB (0.53) | MAOBKDM1AMAOADDB1CRBN | |
| SCHEMBL4337820 | 0.75 | MEN1 (0.63) | MAOBKDM1AMAOADDB1CRBN | |
| Bicarbonate SCHEMBL10974641 | 0.69 | MEN1 (0.50) | MAOBKDM1AMAOAMEN1RAB9A | |
| SCHEMBL1515026 | 0.69 | DRD2 (0.59) | MAOBKDM1AMAOAMEN1KMT2A | |
| SCHEMBL24529592 | 0.68 | ALDH1A1 (0.43) | MAOBKDM1AMAOADDB1CRBN | |
| SCHEMBL17231234 | 0.68 | KDM1A (0.66) | MAOBKDM1AMAOA | |
| SCHEMBL6473377 | 0.68 | OPRM1 (0.47) | MAOBKDM1AMAOAMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003110-B | Aryl beta-aminoketone compound and preparation method thereof | 南京工业大学 | 2022-09-06 | — | — | CN | claimed |
| CN-110003110-B | Aryl beta-aminoketone compound and preparation method thereof | 南京工业大学 | 2022-09-06 | — | — | CN | disclosed |