Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720078 | 0.96 | ESR1 (0.55) | ALDH1A1KMT2AMAPTTHRATHRB | |
| SCHEMBL11714292 | 0.93 | ESR1 (0.54) | ALDH1A1KMT2AMAPTTHRATHRB | |
| SCHEMBL11719155 | 0.89 | KDM4E (0.52) | ALDH1A1THRATHRBKDM4ESMN1; SMN2 | |
| SCHEMBL11717402 | 0.88 | ESR1 (0.54) | KMT2ATHRATHRBSMN1; SMN2ESR1 | |
| SCHEMBL11713999 | 0.87 | THRA (0.51) | KMT2ATHRATHRBLMNAESR1 | |
| SCHEMBL11718537 | 0.87 | LMNA (0.44) | ALDH1A1KMT2AMAPTTHRATHRB | |
| SCHEMBL11720224 | 0.87 | KMT2A (0.49) | KMT2ATHRATHRBLMNAESR1 | |
| SCHEMBL9365125 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTTHRATHRB | |
| SCHEMBL11715619 | 0.85 | ALDH1A1 (0.51) | ALDH1A1THRATHRBKDM4ESMN1; SMN2 | |
| SCHEMBL11720978 | 0.84 | ESR1 (0.58) | KMT2AKDM4ELMNASMN1; SMN2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |