Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.46 |
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719155 | 0.96 | KDM4E (0.52) | ALDH1A1BCHEACHEKDM4ESMN1; SMN2 | |
| SCHEMBL11714062 | 0.93 | ESR1 (0.49) | ALDH1A1BCHEACHEKDM4ESMN1; SMN2 | |
| SCHEMBL11720078 | 0.88 | ESR1 (0.55) | ALDH1A1KDM4ESMN1; SMN2THRATHRB | |
| SCHEMBL6057567 | 0.87 | ALDH1A1 (0.63) | ALDH1A1BCHEACHEKDM4ESMN1; SMN2 | |
| SCHEMBL11717604 | 0.87 | BCHE (0.59) | BCHEACHEHRH3 | |
| SCHEMBL11720107 | 0.86 | ESR1 (0.46) | BCHEACHESMN1; SMN2HRH3LSS | |
| SCHEMBL11712203 | 0.86 | THRA (0.55) | BCHEACHETHRATHRB | |
| SCHEMBL11718751 | 0.86 | BCHE (0.52) | BCHEACHETHRATHRB | |
| SCHEMBL11720909 | 0.85 | ALDH1A1 (0.54) | ALDH1A1BCHEACHEKDM4ESMN1; SMN2 | |
| SCHEMBL11719494 | 0.83 | BCHE (0.58) | BCHEACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010272-A | ANTHELMINTICALLY ACTIVE BASICALLY SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5(6)-PHENYL ETHERS AND -KETONES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |