Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727886 | 0.88 | PGK1 (0.36) | ESR1ESR2PGK1PGK2CYP1A2 | |
| SCHEMBL11728400 | 0.86 | PGK1 (0.41) | ESR1ESR2ALDH1A1CYP3A4CHEK1 | |
| SCHEMBL11733700 | 0.78 | PGK1 (0.35) | ESR1ESR2PGK1PGK2HSD17B10 | |
| SCHEMBL11724415 | 0.74 | NPSR1 (0.37) | ESR1ESR2ALDH1A1CYP3A4CHEK1 | |
| SCHEMBL11730393 | 0.73 | PGK1 (0.41) | PGK1PGK2CYP1A2CYP2D6 | |
| SCHEMBL11723747 | 0.71 | ALDH1A1 (0.33) | ESR1ESR2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL11729751 | 0.70 | KDM4E (0.31) | ALDH1A1PGK1PGK2POLBKDM4E | |
| SCHEMBL11757262 | 0.66 | PTPN1 (0.42) | ESR1ESR2ARPTPN1 | |
| SCHEMBL9512171 | 0.65 | CYP1A2 (0.36) | ESR1ESR2PGK1PGK2CYP1A2 | |
| SCHEMBL24602943 | 0.65 | ALDH1A1 (0.64) | ESR1ESR2ALDH1A1CYP3A4CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017455-A | Polyolefins and polyesters flame-proofed with carboxyalkyl and carbamoylalkyl substituted poly(phosphine oxides) | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-4009207-A | CARBAMOYLALKYL SUBSTITUTED POLY(PHOSPHINE OXIDE) FLAME-RETARDANTS | AMERICAN CYANAMID COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3976685-A | Carboxyalkyl and carbamoylalkyl substituted poly(phosphine oxide) flame-retardants | AMERICAN CYANAMID COMPANY (US) | 1976-08-24 | — | — | US | disclosed |