Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGFR | P43088 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733734 | 0.92 | TBXA2R (0.38) | KDM4EPTGER1PTGFRTBXA2RPTGER3 | |
| SCHEMBL11728728 | 0.88 | ALDH1A1 (0.40) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL11733336 | 0.88 | CYP1A2 (0.48) | KMT2APTGER1PTGFRTBXA2RPTGER3 | |
| SCHEMBL11730106 | 0.86 | TBXA2R (0.53) | PTGER1PTGFRTBXA2RPTGER3PTGDR | |
| SCHEMBL11729925 | 0.85 | LTA4H (0.43) | KDM4EPTGER1PTGFRTBXA2RPTGER3 | |
| SCHEMBL11732380 | 0.81 | GRM2 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL11729979 | 0.80 | RAB9A (0.44) | ALDH1A1PTGER1PTGFRTBXA2RPTGER3 | |
| SCHEMBL11729893 | 0.80 | CA1 (0.44) | — | |
| SCHEMBL11658754 | 0.80 | KDM4E (0.42) | KDM4EKMT2AALDH1A1PTGER1PTGFR | |
| SCHEMBL11725299 | 0.80 | PTGFR (0.43) | ALDH1A1PTGER1PTGFRTBXA2RPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | claimed |
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |