Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 7/20 | 0.33 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HTR2B | P41595 | 5/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735670 | 1.00 | CASP1 (0.34) | CASP1CASP7HSD17B10CRBNHTR2A | |
| SCHEMBL11740282 | 0.73 | DRD1 (0.42) | HTR2ACA9MAPTKMT2AHTR1A | |
| SCHEMBL11740277 | 0.73 | DRD1 (0.42) | HTR2ACA9MAPTKMT2AHTR1A | |
| SCHEMBL448237 | 0.71 | CHRNB2 (0.39) | HTR2AHTR2CPSEN1PSEN2APH1B | |
| SCHEMBL3886540 | 0.68 | ADRA2A (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL27723083 | 0.67 | HTR2C (0.43) | HTR2AHTR2CHTR2B | |
| SCHEMBL11732725 | 0.67 | — | — | |
| SCHEMBL11732714 | 0.67 | — | — | |
| SCHEMBL11533307 | 0.65 | ACHE (0.50) | HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL11533311 | 0.65 | ACHE (0.50) | HTR2AHTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4034095-A | ANTIDEPRESSANT, ANTICHOLINERGIC | SANDOZ LTD. (CH) | 1977-07-05 | — | — | US | claimed |