Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737870 | 0.83 | KDM4E (0.49) | ALDH1A1KDM4EHSD17B10LMNASRD5A2 | |
| SCHEMBL8913109 | 0.81 | SRD5A2 (0.63) | ALDH1A1KDM4EHSD17B10LMNASRD5A2 | |
| SCHEMBL3099146 | 0.77 | CYP2C19 (0.51) | ALDH1A1KDM4EHSD17B10LMNASRD5A2 | |
| SCHEMBL12596312 | 0.77 | SRD5A2 (0.66) | RXRAALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL8544994 | 0.75 | IDO1 (0.47) | ALDH1A1KDM4EHSD17B10LMNASRD5A2 | |
| SCHEMBL4369016 | 0.74 | PLA2G4A (0.67) | PLA2G4AALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL3107966 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10LMNASRD5A2 | |
| SCHEMBL8911576 | 0.72 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10LMNASRD5A2 | |
| SCHEMBL4360657 | 0.72 | PLA2G4A (0.68) | PLA2G4AALDH1A1KDM4EHSD17B10SRD5A2 | |
| SCHEMBL38660125 | 0.72 | KDM4E (0.54) | ALDH1A1KDM4EHSD17B10LMNASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060626-A | Indole-carboxylic carbon compounds and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1977-11-29 | — | — | US | disclosed |