Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856097 | 0.82 | OPRM1 (0.40) | LMNATSHRMAPK1ALDH1A1MEN1 | |
| SCHEMBL28802172 | 0.79 | CTSD (0.35) | LMNATSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL27899553 | 0.77 | TSHR (0.38) | LMNATSHRMAPK1ALDH1A1MEN1 | |
| SCHEMBL29866080 | 0.75 | TSHR (0.39) | LMNATSHRMAPK1ALDH1A1MEN1 | |
| SCHEMBL6158666 | 0.75 | TSHR (0.39) | LMNATSHRMAPK1ALDH1A1MEN1 | |
| SCHEMBL507495 | 0.75 | SMN1; SMN2 (0.44) | LMNATSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL29793660 | 0.75 | SMN1; SMN2 (0.44) | LMNATSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL1706213 | 0.74 | MTNR1A (0.36) | LMNATSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL1706364 | 0.74 | AKR1B1 (0.43) | LMNATSHRALDH1A1CYP1A2NFKB1 | |
| SCHEMBL3321567 | 0.73 | RXRA (0.37) | LMNATSHRMAPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051261-A | HYPOLIPIDEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1977-09-27 | — | — | US | disclosed |