Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 3/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117217 | 1.00 | TACR3 (0.62) | TACR3RXFP1TP53KDM4EALDH1A1 | |
| SCHEMBL6451947 | 0.78 | TACR3 (1.00) | TACR3KDM4EALDH1A1 | |
| SCHEMBL7532008 | 0.78 | TACR3 (1.00) | TACR3KDM4EALDH1A1 | |
| SCHEMBL116047 | 0.76 | EPRS1 (0.63) | ALDH1A1 | |
| SCHEMBL8619775 | 0.73 | PPARA (0.64) | KDM4EALDH1A1PKM | |
| SCHEMBL117389 | 0.71 | DHODH (0.48) | RXFP1TP53 | |
| SCHEMBL8618914 | 0.71 | CYP2C9 (0.46) | RXFP1TP53ALDH1A1 | |
| SCHEMBL15145372 | 0.70 | ALDH1A1 (0.55) | TACR3KDM4EALDH1A1PKM | |
| SCHEMBL15145366 | 0.70 | ALDH1A1 (0.55) | TACR3KDM4EALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL8619359 | 0.70 | CYP2C9 (0.46) | RXFP1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058133-A1 | INHIBITION OF TRNA SYNTHETASES AND THERAPEUTIC APPLICATIONS THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058133-A1 | INHIBITION OF TRNA SYNTHETASES AND THERAPEUTIC APPLICATIONS THEREOF | AARS1, GARS1, TRMT1 | TACR3 4284/4885RXFP1 1205/4885TP53 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.