Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267275 | 0.83 | TSHR (0.44) | TSHRCYP3A4ALDH1A1LMNAAGTR1 | |
| SCHEMBL11189916 | 0.83 | TSHR (0.72) | TSHRCYP3A4ALDH1A1LMNAMAPK1 | |
| SCHEMBL11188342 | 0.82 | L3MBTL1 (0.53) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL3208138 | 0.81 | L3MBTL1 (0.58) | ALDH1A1LMNAL3MBTL1TDP1HPGD | |
| SCHEMBL11901213 | 0.79 | TSHR (0.62) | TSHRCYP3A4ALDH1A1LMNAAGTR1 | |
| SCHEMBL9687621 | 0.78 | TSHR (0.64) | TSHRCYP3A4ALDH1A1LMNAAGTR1 | |
| SCHEMBL11406237 | 0.78 | HPGD (0.68) | ALDH1A1LMNASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL11414746 | 0.78 | MASP2 (0.57) | TSHRCYP3A4ALDH1A1LMNAMAPK1 | |
| SCHEMBL8329482 | 0.77 | L3MBTL1 (0.58) | ALDH1A1LMNAAGTR1MAPK1SMN1; SMN2 | |
| SCHEMBL2960968 | 0.77 | ALDH1A1 (0.61) | TSHRCYP3A4ALDH1A1LMNAAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042603-A | SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE | UBE INDUSTRIES, LTD. (JA) | 1977-08-16 | — | — | US | disclosed |