Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29864864 | 0.89 | TSHR (0.62) | ALDH1A1TDP1TSHRCYP3A4HPRT1 | |
| SCHEMBL4259701 | 0.89 | TSHR (0.62) | ALDH1A1TDP1TSHRCYP3A4HPRT1 | |
| SCHEMBL2960948 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TDP1TSHRCYP3A4HPRT1 | |
| SCHEMBL11189916 | 0.85 | TSHR (0.72) | ALDH1A1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL27930471 | 0.83 | TSHR (0.59) | ALDH1A1TDP1TSHRCYP3A4HPRT1 | |
| SCHEMBL3538142 | 0.83 | TSHR (0.55) | ALDH1A1TDP1TSHRCYP3A4HPRT1 | |
| SCHEMBL4464974 | 0.83 | TSHR (0.55) | ALDH1A1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL12722617 | 0.83 | TSHR (0.55) | TSHRCYP3A4HPRT1MAPTLMNA | |
| SCHEMBL3276362 | 0.81 | TDP1 (0.66) | ALDH1A1TDP1HPRT1MAPTLMNA | |
| SCHEMBL30352851 | 0.81 | TDP1 (0.66) | ALDH1A1TDP1HPRT1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |
| CN-105061296-A | Preparation method for 2-substituted carbazole compounds | ZHANGJIAGANG IND TECHNOLOGY RES INST JIANGSU UNIVERSITY OF SCIENCE AND TECHNOLOGY | 2015-11-18 | — | — | CN | disclosed |
| US-20130200357-A1 | FORMULATIONS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-08 | — | — | US | disclosed |
| US-8343637-B2 | Carbazole derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-01-01 | — | — | US | disclosed |
| US-8338605-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2012-12-25 | — | — | US | disclosed |
| CN-102702194-A | Anti-viral compounds | ABBOTT LAB | 2012-10-03 | — | — | CN | disclosed |
| CN-102267848-A | Method for synthesizing biphenol compound by catalyzing Suzuki coupling reaction with nanometer palladium catalyst | — | 2011-12-07 | — | — | CN | disclosed |
| US-20100256139-A1 | Anti-Viral Compounds | ABBOTT LABORATORIES (US) | 2010-10-07 | — | — | US | disclosed |
| EP-1979349-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2010-07-28 | — | — | EP | disclosed |
| US-7763731-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2010-07-27 | — | — | US | disclosed |
| CN-1028755-C | Azole derivate, manufacturing method and application thereof | HOECHST AG (DE) | 1995-06-07 | — | — | CN | disclosed |
| US-5310737-A | Benzo-fused lactams that promote the release of growth hormone | MERCK & CO., INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5206235-A | Animal growth regulators; stimulants | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |
| CN-1066844-A | Pyrrole derivative, their preparation method and application | HOECHST AG (DE) | 1992-12-09 | — | — | CN | disclosed |
| EP-0513974-A1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| CN-1066070-A | Promote the new benzo-fused lactams that tethelin discharges | MERCK & CO INC (US) | 1992-11-11 | — | — | CN | disclosed |
| WO-1992016524-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |
| US-4422979-A | Fluoro-substituted biphenylyl compounds and processes | ETHYL CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |
| US-4371473-A | Preparation of 2-(2-fluoro-4-biphenylyl)propionic acid and corresponding nitride | ETHYL CORPORATION (US) | 1983-02-01 | — | — | US | disclosed |
| US-4278516-A | Method for the preparation of 2-fluoro-4-monobromomethylbiphenyl | ETHYL CORPORATION (US) | 1981-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256139-A1 | Anti-Viral Compounds | HAVCR2, MAVS, EIF2AK2 | ALDH1A1 2723/4885TDP1 4336/4885TSHR 4805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.