Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.41 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 11/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231895 | 1.00 | MAOA (0.41) | MAOAKDM1AMAOBCYP2D6CYP2C19 | |
| SCHEMBL1720274 | 0.90 | NPC1 (0.37) | MAOAKDM1AMAOB | |
| SCHEMBL4243945 | 0.82 | MAOA (0.38) | MAOAKDM1AMAOBCYP2D6CYP2C19 | |
| SCHEMBL4948662 | 0.82 | ESR2 (0.39) | CYP2D6CYP2C19P2RX7 | |
| SCHEMBL1720397 | 0.80 | SLC6A4 (0.39) | KDM1A | |
| SCHEMBL14667575 | 0.80 | MAOB (0.44) | MAOAKDM1AMAOB | |
| SCHEMBL11740261 | 0.77 | MAOB (0.36) | MAOAKDM1AMAOB | |
| SCHEMBL1733173 | 0.76 | TAAR1 (0.35) | KDM1ACYP2D6CYP2C19P2RX7 | |
| SCHEMBL1733751 | 0.76 | BACE1 (0.34) | CYP2D6CYP2C19P2RX7 | |
| SCHEMBL1733040 | 0.76 | HTR2A (0.36) | KDM1ACYP2D6CYP2C19P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846890-B2 | Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization | JSR CORPORATION (JP) | 2005-01-25 | — | — | US | disclosed |