Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11744846 | 0.87 | L3MBTL1 (0.51) | L3MBTL1SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL11633475 | 0.85 | L3MBTL1 (0.45) | L3MBTL1SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL11630716 | 0.84 | RAD52 (0.43) | L3MBTL1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL11632571 | 0.83 | L3MBTL1 (0.43) | L3MBTL1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL11812209 | 0.81 | DRD2 (0.53) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11630749 | 0.81 | L3MBTL1 (0.50) | L3MBTL1DRD2HTR2ALMNAKDM4E | |
| SCHEMBL11634610 | 0.80 | L3MBTL1 (0.45) | L3MBTL1SLC6A2SLC6A4HTR1ADRD2 | |
| SCHEMBL11633185 | 0.80 | L3MBTL1 (0.47) | L3MBTL1SLC6A4HTR1ADRD2HTR2A | |
| SCHEMBL11628508 | 0.80 | L3MBTL1 (0.41) | L3MBTL1FPR2PROKR1HTR1ADRD2 | |
| SCHEMBL11631967 | 0.79 | L3MBTL1 (0.48) | L3MBTL1DRD2HTR2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |