Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804452 | 0.81 | HTR1A (0.48) | LMNAMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL11744846 | 0.81 | L3MBTL1 (0.51) | L3MBTL1LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL11632587 | 0.80 | L3MBTL1 (0.50) | L3MBTL1LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL11634977 | 0.80 | L3MBTL1 (0.47) | L3MBTL1LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL11741206 | 0.80 | L3MBTL1 (0.46) | L3MBTL1LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL11633969 | 0.79 | L3MBTL1 (0.47) | L3MBTL1LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL11629904 | 0.78 | L3MBTL1 (0.47) | L3MBTL1LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL11631327 | 0.78 | L3MBTL1 (0.49) | L3MBTL1LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL11632571 | 0.77 | L3MBTL1 (0.43) | L3MBTL1LMNAMAPTALDH1A1RAB9A | |
| SCHEMBL11631833 | 0.77 | L3MBTL1 (0.44) | L3MBTL1LMNAMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |