Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.30 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737201 | 0.84 | NPSR1 (0.33) | SMN1; SMN2NPSR1POLBALDH1A1KDM4E | |
| SCHEMBL5143956 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2POLBCDK2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11743005 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2CDK2ALDH1A1KDM4EHPGD | |
| Bromide SCHEMBL11739645 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2CDK2ALDH1A1KDM4EHPGD | |
| SCHEMBL11738008 | 0.77 | GLP1R (0.37) | SMN1; SMN2CDK2ALDH1A1L3MBTL1 | |
| SCHEMBL11723495 | 0.75 | CCNE2 (0.33) | SLC29A1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL11723530 | 0.70 | CCNE2 (0.32) | SLC29A1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL11733104 | 0.69 | POLB (0.42) | SMN1; SMN2POLBCDK2ALDH1A1KDM4E | |
| SCHEMBL11739718 | 0.65 | ALDH1A1 (0.37) | SLC29A1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL26538070 | 0.65 | MAPT (0.41) | POLBALDH1A1KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052510-A | 4-ALKYL-2,6-DI(SECONDARY OR TERTIARY ALKYLAMINO) PYRIDINES, COMPOSITIONS THEREOF AND METHODS FOR TREATING DIABETES AND OBESITY | SANDOZ, INC. (US) | 1977-10-04 | — | — | US | disclosed |