Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | RPS27 | P42677 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11739645 | 0.98 | SMN1; SMN2 (0.34) | SMN1; SMN2CCNA2CDK2TTKRPS27 | |
| Hydrochloric Acid SCHEMBL11743005 | 0.98 | SMN1; SMN2 (0.34) | SMN1; SMN2CCNA2CDK2TTKRPS27 | |
| SCHEMBL11738008 | 0.94 | GLP1R (0.37) | SMN1; SMN2CCNA2CDK2TTKRPS27 | |
| SCHEMBL11733104 | 0.86 | POLB (0.42) | SMN1; SMN2CCNA2CDK2TTKRPS27 | |
| SCHEMBL11740878 | 0.84 | CYP3A4 (0.41) | CCNA2CDK2TTKRPS27MAPK8 | |
| SCHEMBL11744059 | 0.82 | SLC29A1 (0.34) | SMN1; SMN2CDK2KDM4EALDH1A1LMNA | |
| SCHEMBL11738829 | 0.81 | ALDH1A1 (0.40) | CDK2MAPTALDH1A1HTT | |
| SCHEMBL11737201 | 0.80 | NPSR1 (0.33) | SMN1; SMN2MAPK8KDM4EALDH1A1LMNA | |
| SCHEMBL17393535 | 0.74 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL11716065 | 0.72 | GLP1R (0.35) | CDK2GLP1RLMNAPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| US-20070072096-A1 | Negative curable dye-containing composition, color filter, and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| EP-0483249-B1 | METHOD OF TRANSCRIPTIONALLY MODULATING GENE EXPRESSION AND OF DISCOVERING CHEMICALS CAPABLE OF FUNCTIONING AS GENE EXPRESSION MODULATORS | OSI PHARM INC (US) | 2003-04-23 | — | — | EP | disclosed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | disclosed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | disclosed |
| US-5665543-A | Method of discovering chemicals capable of functioning as gene expression modulators | ONCOGENE SCIENCE, INC. (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0483249-A4 | — | — | 1994-04-06 | — | — | EP | disclosed |
| WO-1992012635-A1 | METHODS OF TRANSCRIPTIONALLY MODULATING GENE EXPRESSION OF VIRAL GENES AND OTHER GENES | ONCOGENE SCIENCE, INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| WO-1992013092-A1 | METHODS OF TRANSCRIPTIONALLY MODULATING EXPRESSION OF HEMATOPOIETIC GROWTH FACTOR GENES | ONCOGENE SCIENCE, INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| WO-1992013063-A1 | METHODS OF TRANSCRIPTIONALLY MODULATING EXPRESSION OF GROWTH FACTOR GENES AND GROWTH FACTOR RECEPTOR GENES | ONCOGENE SCIENCE, INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| EP-0483249-A1 | METHOD OF TRANSCRIPTIONALLY MODULATING GENE EXPRESSION AND OF DISCOVERING CHEMICALS CAPABLE OF FUNCTIONING AS GENE EXPRESSION MODULATORS | Oncogene Science, Inc. (US) | 1992-05-06 | — | — | EP | disclosed |
| WO-1991001379-A1 | METHOD OF TRANSCRIPTIONALLY MODULATING GENE EXPRESSION AND OF DISCOVERING CHEMICALS CAPABLE OF FUNCTIONING AS GENE EXPRESSION MODULATORS | ONCOGENE SCIENCE, INC. (US) | 1991-02-07 | — | — | WO | disclosed |
| US-4052510-A | 4-ALKYL-2,6-DI(SECONDARY OR TERTIARY ALKYLAMINO) PYRIDINES, COMPOSITIONS THEREOF AND METHODS FOR TREATING DIABETES AND OBESITY | SANDOZ, INC. (US) | 1977-10-04 | — | — | US | disclosed |