Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 8/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.49 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746806 | 0.88 | CTSL (0.71) | CTSLCA2PTPN1ITGB3ITGA2B | |
| SCHEMBL10802837 | 0.88 | CTSL (0.71) | CTSLCA2PTPN1ITGB3ITGA2B | |
| SCHEMBL11745003 | 0.88 | CA2 (0.69) | CTSLCA2PTPN1ITGB3ITGA2B | |
| SCHEMBL11744597 | 0.88 | CA2 (0.63) | CTSLCA2PTPN1ITGB3ITGA2B | |
| SCHEMBL11751332 | 0.88 | CTSL (0.60) | CTSLCA2PTPN1ITGB3ITGA2B | |
| SCHEMBL11746757 | 0.85 | PRSS1 (0.58) | CTSLCA2PTPN1ITGB3ITGA2B | |
| SCHEMBL12029785 | 0.85 | CTSL (0.58) | CTSLCA2PTPN1ITGB3ITGA2B | |
| SCHEMBL11747136 | 0.83 | CA2 (0.67) | CTSLCA2PTPN1ITGB3ITGA2B | |
| SCHEMBL1122708 | 0.82 | GPR132 (0.69) | PTPN1ITGB3ITGA2BGPR132 | |
| SCHEMBL12029822 | 0.82 | CA2 (0.62) | CTSLCA2PTPN1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |