Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796945 | 0.77 | SIGMAR1 (0.46) | HTR2ACYP3A4MEN1CYP2D6ALOX15 | |
| SCHEMBL29415514 | 0.77 | ALDH1A1 (0.46) | HTR2CHTR2AGAASMN1; SMN2 | |
| SCHEMBL2139658 | 0.77 | ALDH1A1 (0.46) | HTR2CHTR2AGAASMN1; SMN2 | |
| SCHEMBL30027759 | 0.77 | ALDH1A1 (0.46) | HTR2CHTR2AGAASMN1; SMN2 | |
| SCHEMBL23505845 | 0.75 | HTR2C (0.38) | HTR2CHTR2ACYP3A4MEN1CYP2D6 | |
| SCHEMBL1508195 | 0.75 | PGR (0.44) | HTR2CHTR2AALOX15TSHRMAPK1 | |
| SCHEMBL29809193 | 0.75 | HTR2A (0.41) | HTR2CHTR2ACYP3A4MEN1CYP2D6 | |
| SCHEMBL192411 | 0.75 | HTR2A (0.41) | HTR2CHTR2ACYP3A4MEN1CYP2D6 | |
| SCHEMBL14101425 | 0.75 | PGR (0.44) | HTR2CHTR2AALOX15TSHRMAPK1 | |
| SCHEMBL193611 | 0.75 | HTR2A (0.41) | HTR2CHTR2ACYP3A4MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923021-B | It is suitable for the heteroaryl compound of E1 activating enzyme inhibitors | 米伦纽姆医药公司 | 2018-03-30 | — | — | CN | disclosed |
| US-4013682-A | N-HYDROXY-AMIDINE COMPOUNDS | AKZONA INCORPORATED (US) | 1977-03-22 | — | — | US | disclosed |
| US-3978126-A | N-HYDROXY-AMIDINE COMPOUNDS | AKZONA INCORPORATED (US) | 1976-08-31 | — | — | US | disclosed |