Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614949 | 0.84 | APP (0.61) | SGMS2ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL13052998 | 0.78 | ALDH1A1 (0.52) | SGMS2ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL31503554 | 0.78 | MAOB (0.59) | SGMS2ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL592290 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HPGDKMT2AF2RAB9A | |
| SCHEMBL219488 | 0.78 | NPC1 (0.61) | SGMS2ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL11649490 | 0.78 | NPC1 (0.64) | ALDH1A1HPGDKMT2ARAB9ANPC1 | |
| SCHEMBL9867688 | 0.77 | SGMS2 (0.55) | SGMS2ALDH1A1HPGDKMT2AF2 | |
| SCHEMBL12639231 | 0.77 | RAB9A (0.74) | ALDH1A1HPGDKMT2AF2RAB9A | |
| SCHEMBL26833293 | 0.77 | ALDH1A1 (0.49) | SGMS2ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL14266181 | 0.76 | ALDH1A1 (0.64) | ALDH1A1HPGDKMT2AF2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038396-A | ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1977-07-26 | — | — | US | claimed |