SCHEMBL31503554

SCHEMBL31503554

Clc1cccc(-c2nc3cccnc3o2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.59
SGMS2 Q8NHU3 1/20 0.56
SMN1; SMN2 Q16637 5/20 0.48
TP53 P04637 4/20 0.48
NPC1 O15118 4/20 0.48
RAB9A P51151 4/20 0.48
MAPT P10636 2/20 0.48
TSHR P16473 2/20 0.48
MITF O75030 1/20 0.48
PKM P14618 1/20 0.48
GRM5 P41594 1/20 0.48
NPSR1 Q6W5P4 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9868635 0.83 HPGD (0.54) MAOBSGMS2SMN1; SMN2TP53NPC1
SCHEMBL13052998 0.82 ALDH1A1 (0.52) SGMS2SMN1; SMN2TP53NPC1RAB9A
SCHEMBL219488 0.82 NPC1 (0.61) SGMS2SMN1; SMN2TP53NPC1RAB9A
SCHEMBL27200963 0.81 HPGD (0.53) MAOBSGMS2SMN1; SMN2TP53NPC1
SCHEMBL9867688 0.80 SGMS2 (0.55) MAOBSGMS2SMN1; SMN2TP53NPC1
SCHEMBL14693756 0.80 MAOB (0.68) MAOBSMN1; SMN2TP53NPC1RAB9A
SCHEMBL13998685 0.79 ALDH1A1 (0.59) MAOBSGMS2SMN1; SMN2TP53NPC1
SCHEMBL11745194 0.78 SGMS2 (0.60) SGMS2SMN1; SMN2TP53NPC1RAB9A
SCHEMBL12910410 0.78 HPGD (0.56) SGMS2SMN1; SMN2TP53NPC1RAB9A
SCHEMBL26535807 0.77 SMN1; SMN2 (0.44) SGMS2SMN1; SMN2TP53NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025084253-A1 CARBAZOLE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2025-04-24 WO disclosed