Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.37 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.37 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11744435 | 0.79 | BRPF1 (0.55) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11536976 | 0.68 | CHEK1 (0.66) | PARP10PARP2PARP15TNKS2TNKS | |
| Hydrochloric Acid SCHEMBL11747896 | 0.67 | CHEK1 (0.64) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11852619 | 0.64 | PARP10 (0.39) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11748057 | 0.63 | BRPF1 (0.53) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11532017 | 0.63 | PARP2 (0.53) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11537172 | 0.62 | DCTPP1 (0.34) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL4023863 | 0.56 | CDK2 (0.34) | CDK2CDK1CCNB1 | |
| SCHEMBL23030303 | 0.55 | KDM4E (0.38) | HSD17B10KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL12109863 | 0.54 | NPC1 (0.49) | HSD17B10KDM4EALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064261-A | TRIAZOLOBENOXAZOLE, TRIAZOLOBENZOTHIAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |