Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178468 | 0.85 | ALDH1A1 (0.53) | PPARGPPARANPSR1HTR2AHTR2C | |
| SCHEMBL11291464 | 0.81 | PPARG (0.49) | PPARGPPARANPSR1HTR2AHTR2C | |
| SCHEMBL17911612 | 0.80 | MTNR1A (0.40) | NPSR1KDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL30605888 | 0.79 | NPSR1 (0.57) | PPARGPPARANPSR1KDM4EL3MBTL1 | |
| SCHEMBL16414897 | 0.79 | PPARG (0.50) | PPARGPPARANPSR1HTR2AHTR2C | |
| SCHEMBL20819554 | 0.79 | EDNRB (0.35) | PPARGPPARAMAPTCYP2C19 | |
| SCHEMBL3720175 | 0.79 | HDAC8 (0.41) | ALDH1A1GAAMAPT | |
| SCHEMBL24342044 | 0.78 | PPARG (0.52) | PPARGPPARANPSR1HTR2AHTR2C | |
| SCHEMBL14227150 | 0.78 | PPARG (0.46) | PPARGPPARANPSR1HTR2AHTR2C | |
| SCHEMBL6550208 | 0.78 | PPARG (0.59) | PPARGPPARANPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4027028-A | HYPOTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1977-05-31 | — | — | US | disclosed |