Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750227 | 1.00 | LMNA (0.59) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL5530041 | 0.94 | ALDH1A1 (0.61) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11751772 | 0.89 | ALOX5 (0.58) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11751223 | 0.89 | ALOX5 (0.58) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11753179 | 0.87 | ALDH1A1 (0.60) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7054803 | 0.86 | ALDH1A1 (0.54) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11755156 | 0.85 | LMNA (0.48) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11751969 | 0.85 | LMNA (0.48) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11753624 | 0.85 | ADORA2A (0.50) | LMNAALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL11750818 | 0.85 | NFKB1 (0.50) | LMNAALDH1A1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |