Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748397 | 0.85 | LMNA (0.59) | LMNAALDH1A1KDM4EMAPTPTGS2 | |
| SCHEMBL11750227 | 0.85 | LMNA (0.59) | LMNAALDH1A1KDM4EMAPTPTGS2 | |
| SCHEMBL5530041 | 0.85 | ALDH1A1 (0.61) | LMNAALDH1A1KDM4EMAPTPTGS2 | |
| SCHEMBL11747674 | 0.84 | PTGS2 (0.49) | ALDH1A1KDM4EMAPTPTGS2KMT2A | |
| SCHEMBL11751772 | 0.81 | ALOX5 (0.58) | LMNAALDH1A1KDM4EMAPTPTGS2 | |
| SCHEMBL11751223 | 0.81 | ALOX5 (0.58) | LMNAALDH1A1KDM4EMAPTPTGS2 | |
| SCHEMBL11752695 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EMAPTPTGS2KMT2A | |
| SCHEMBL11755609 | 0.78 | HPGD (0.42) | ALDH1A1KDM4EPTGS2L3MBTL1TDP1 | |
| SCHEMBL7054803 | 0.78 | ALDH1A1 (0.54) | LMNAALDH1A1KDM4EMAPTPTGS2 | |
| SCHEMBL11751969 | 0.78 | LMNA (0.48) | LMNAALDH1A1KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |