Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 10/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367849 | 0.82 | TTR (0.54) | TTRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2808430 | 0.81 | TTR (0.72) | TTRAKR1B1MEN1KMT2AKDM4E | |
| SCHEMBL29415448 | 0.81 | TTR (0.72) | TTRAKR1B1MEN1KMT2AKDM4E | |
| SCHEMBL68189 | 0.81 | TTR (0.83) | TTRAKR1B1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL11749391 | 0.80 | TTR (0.81) | TTRAKR1B1MEN1KMT2AKDM4E | |
| SCHEMBL71110 | 0.76 | TTR (0.68) | TTRAKR1B1MEN1KMT2AKDM4E | |
| SCHEMBL11859810 | 0.75 | TTR (0.89) | TTRAKR1B1MEN1KMT2AKDM4E | |
| SCHEMBL11322640 | 0.75 | TTR (0.80) | TTRAKR1B1MEN1KMT2AKDM4E | |
| SCHEMBL21313809 | 0.74 | TTR (0.71) | TTRAKR1B1MEN1KMT2AKDM4E | |
| SCHEMBL1787556 | 0.74 | TTR (1.00) | TTRAKR1B1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3957986-A | Antiviral compositions containing bis-basic esters and amides of xanthene and xanthone | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3953602-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-04-27 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |