Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16931286 | 0.84 | POLB (0.39) | TDP2TLR4KDM4EALDH1A1MAPT | |
| SCHEMBL4768534 | 0.73 | TDP2 (0.39) | TDP2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL30485522 | 0.73 | KDM4E (0.44) | TDP2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL14902253 | 0.72 | — | — | |
| SCHEMBL15228648 | 0.72 | POLB (0.39) | TDP2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL9724627 | 0.71 | CYP1A2 (0.41) | ALDH1A1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL354474 | 0.71 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9782199 | 0.70 | MAPT (0.47) | TLR4KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL10831751 | 0.70 | L3MBTL1 (0.39) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23732676 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003911-A | ANTISECRETORY AGENTS, OXYTOCICS, BRONCHODILATORS, PLASTICIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-18 | — | — | US | disclosed |