Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 10/20 | 0.40 |
| ▸ | WNT3A | P56704 | 8/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677514 | 0.84 | MAPT (0.53) | CTNNB1WNT3ATRPA1ALDH1A1KDM4E | |
| SCHEMBL6836837 | 0.80 | CTNNB1 (0.43) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL11863346 | 0.80 | OPRK1 (0.36) | HPGDCTNNB1WNT3ATRPA1KDM4E | |
| SCHEMBL11798123 | 0.79 | ALDH1A1 (0.43) | HPGDCTNNB1WNT3AALDH1A1KDM4E | |
| SCHEMBL11750545 | 0.79 | ALDH1A1 (0.49) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL11733551 | 0.78 | CTNNB1 (0.42) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL11550231 | 0.78 | TTR (0.40) | HPGDCTNNB1WNT3ATRPA1ALDH1A1 | |
| SCHEMBL11801328 | 0.77 | CTNNB1 (0.41) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL11800787 | 0.76 | ABCC4 (0.35) | HPGDTAS1R3TAS1R1ALDH1A1KDM4E | |
| SCHEMBL19253135 | 0.75 | KDM4E (0.49) | HPGDTAS1R3TAS1R1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |