Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 15/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755440 | 0.83 | P2RX7 (0.33) | CYP19A1 | |
| SCHEMBL17450408 | 0.75 | MEN1 (0.40) | S1PR1S1PR3S1PR5S1PR4CYP19A1 | |
| SCHEMBL7437496 | 0.68 | FAAH (0.35) | CYP19A1FAAHMGLL | |
| SCHEMBL14896329 | 0.64 | ALDH1A1 (0.39) | FAAHMGLL | |
| SCHEMBL16685025 | 0.64 | FAAH (0.38) | CYP19A1FAAHMGLL | |
| SCHEMBL23365641 | 0.63 | FAAH (0.50) | CYP19A1FAAHMGLL | |
| SCHEMBL4094110 | 0.61 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL4094707 | 0.61 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL20245283 | 0.61 | PLA2G7 (0.50) | CYP19A1FAAHMGLL | |
| SCHEMBL5963786 | 0.60 | MGLL (0.61) | CYP19A1FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4034086-A | TREATMENT OF DISEASES RELATED TO ABNORMAL DEPOSITION OR DISSOLUTION OF DIFFICULTY SOLUBLE CALCIUM SALTS | HENKEL & CIE G.M.B.H. (DT) | 1977-07-05 | — | — | US | disclosed |
| US-3960888-A | TOOTHPASTES, MOUTHWASHES, SEQUESTERING AGENT, STABILIZER | HENKEL & CIE G.M.B.H. (DT) | 1976-06-01 | — | — | US | disclosed |