Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851784 | 0.80 | POLB (0.34) | — | |
| SCHEMBL31235575 | 0.77 | MT-CO2 (0.33) | AADAT | |
| SCHEMBL1408376 | 0.74 | MAPT (0.35) | — | |
| SCHEMBL1518987 | 0.72 | ADAM17 (0.32) | — | |
| SCHEMBL5881899 | 0.72 | APEX1 (0.33) | AADAT | |
| SCHEMBL20756411 | 0.72 | — | — | |
| SCHEMBL8158871 | 0.71 | AADAT (0.32) | AADAT | |
| SCHEMBL7767003 | 0.71 | KDM4E (0.40) | — | |
| SCHEMBL10344448 | 0.69 | MAPK1 (0.39) | — | |
| SCHEMBL7203585 | 0.68 | BRD4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150247863-A1 | DERIVATIVES OF 1,2-DIHYDRO-7-HYDROXYQUINOLINES CONTAINING FUSED RINGS | Life Technologies Corporation | 2015-09-03 | — | — | US | disclosed |
| US-20140356873-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | LIFE TECHNOLOGIES CORP (US) | 2014-12-04 | — | — | US | disclosed |
| US-8846925-B2 | Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings | Life Technologies Corporation (US) | 2014-09-30 | — | — | US | disclosed |
| US-20120315661-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | Life Technologies Corporation (US) | 2012-12-13 | — | — | US | disclosed |
| US-8183375-B2 | Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings | Life Technologies Corporation (US) | 2012-05-22 | — | — | US | disclosed |
| US-20110027800-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | Life Technologies Corporation (US) | 2011-02-03 | — | — | US | disclosed |
| US-7816519-B2 | longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond; fluorescent dyes, chemically reactive dyes, dye-conjugates; use of such dyes in staining samples and detecting ligands | Life Technologies Corporation (US) | 2010-10-19 | — | — | US | disclosed |
| US-20070093652-A1 | longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond; fluorescent dyes, chemically reactive dyes, dye-conjugates; use of such dyes in staining samples and detecting ligands | INVITROGEN CORPORATION (US) | 2007-04-26 | — | — | US | disclosed |
| US-7169922-B2 | Longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond | INVITROGEN CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040147747-A1 | Longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond | MOLECULAR PROBES, INC. | 2004-07-29 | — | — | US | disclosed |
| US-5190864-A | Support-leash-enzyme conjugates, small amount of free enzyme releases large amount of bound enzyme | NORTHEASTERN UNIVERSITY (US) | 1993-03-02 | — | — | US | disclosed |
| US-4937188-A | Enzyme activity amplification method for increasing assay sensitivity | NORTHEASTERN UNIVERSITY (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0243797-A2 | Method for amplifying enzyme activity, enzyme conjugates suitable therefor and their preparation | NORTHEASTERN UNIVERSITY (US) | 1987-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110027800-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | CYP3A7, UGT1A7, UGT2B7 | AADAT 3039/4885 |
| US-20070093652-A1 | longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond; fluorescent dyes, chemically reactive dyes, dye-conjugates; use of such dyes in staining samples and detecting ligands | CYP3A4, CYP3A5, UGT1A4 | AADAT 2287/4885 |
| US-20150247863-A1 | DERIVATIVES OF 1,2-DIHYDRO-7-HYDROXYQUINOLINES CONTAINING FUSED RINGS | CYP3A7, UGT1A7, UGT2B7 | AADAT 3039/4885 |
| US-20140356873-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | CYP3A7, UGT1A7, UGT2B7 | AADAT 3039/4885 |
| US-20040147747-A1 | Longer wavelength absorption than structurally similar dyes; staining; ligand and analyte detection; aromatic or heteroaromatic ring fused at 3,4-double bond | CYP3A4, CYP3A5, UGT1A4 | AADAT 1868/4885 |
| US-20120315661-A1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings | CYP3A7, UGT1A7, UGT2B7 | AADAT 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.