Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 4/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | CD40 | P25942 | 1/20 | 0.46 |
| ▸ | CD40LG | P29965 | 1/20 | 0.46 |
| ▸ | FGF1 | P05230 | 1/20 | 0.44 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760881 | 0.97 | TIMP3 (0.52) | TIMP3SIRT1CD40CD40LGFGF1 | |
| SCHEMBL11347286 | 0.90 | TIMP3 (0.49) | TIMP3SIRT1CD40CD40LGFGF1 | |
| SCHEMBL11339195 | 0.89 | TIMP3 (0.48) | TIMP3SIRT1CD40CD40LGFGF1 | |
| SCHEMBL11766235 | 0.88 | KMT2A (0.54) | TIMP3SIRT1HPSEMEN1KMT2A | |
| SCHEMBL11766279 | 0.85 | KMT2A (0.56) | TIMP3SIRT1HPSEMEN1KMT2A | |
| SCHEMBL11338609 | 0.82 | PRMT1 (0.49) | TIMP3SIRT1CD40CD40LGFGF1 | |
| SCHEMBL10907712 | 0.82 | MPL (0.46) | TIMP3CD40CD40LGMEN1KMT2A | |
| SCHEMBL10907905 | 0.81 | MPL (0.48) | TIMP3CD40CD40LGMEN1KMT2A | |
| SCHEMBL11355263 | 0.81 | TIMP3 (0.54) | TIMP3SIRT1CD40CD40LGFGF1 | |
| SCHEMBL11341156 | 0.81 | TIMP3 (0.48) | TIMP3SIRT1CD40CD40LGFGF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4027038-A | NAPHTHALENEDISULFONIC ACID UREIDES | AMERICAN CYANAMID COMPANY (US) | 1977-05-31 | — | — | US | disclosed |