SCHEMBL7790539

SCHEMBL7790539

Nc1ccc2cc(S(=O)(=O)O)cc(O)c2c1/N=N/c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SENP2 Q9HC62 3/20 0.68
▸ SUMO2 P61956 2/20 0.68
▸ SUMO1 P63165 2/20 0.68
▸ SENP7 Q9BQF6 2/20 0.68
▸ ENPP2 Q13822 4/20 0.57
▸ CYP1A2 P05177 3/20 0.53
▸ APEX1 P27695 3/20 0.51
▸ MAPK1 P28482 3/20 0.50
▸ NT5E P21589 2/20 0.50
▸ GAA P10253 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ APP P05067 1/20 0.50
▸ PHLPP2 Q6ZVD8 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ CYP2C9 P11712 2/20 0.46
▸ SENP3 Q9H4L4 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790541 1.00 SENP2 (0.68) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL11765859 0.91 SUMO2 (0.81) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL11765850 0.91 SUMO2 (0.81) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL10941472 0.90 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL14418348 0.90 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL10941468 0.90 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL26459720 0.90 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL11670234 0.89 SUMO2 (0.74) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL12955196 0.88 SENP2 (0.60) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL11670202 0.88 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108366943-B Hair treatment method 花王株式会社 2022-01-25 — — CN disclosed
EP-3395323-B1 METHOD FOR TREATING HAIR KAO CORP (JP) 2021-09-29 — — EP disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 — — US disclosed
EP-3395323-A1 HAIR TREATMENT METHOD Kao Corporation (JP) 2018-10-31 — — EP disclosed
US-7456237-B2 Colorant-containing curable composition, color filter and method of producing the same FUJIFILM CORPORATION (JP) 2008-11-25 — — US disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 — — EP disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 — — EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 — — US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 — — EP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 — — US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 — — EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 — — EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 — — EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 — — WO disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 SENP2 3494/4885SUMO2 2458/4885SUMO1 2777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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