Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176646 | 0.83 | ESRRA (0.57) | ESRRARAB9AMEN1KMT2ANPC1 | |
| SCHEMBL1176794 | 0.76 | ALDH1A1 (0.41) | ESRRAMEN1KMT2AKDM4EGAA | |
| SCHEMBL1176632 | 0.73 | RAB9A (0.65) | RAB9AMEN1KMT2ANPC1KDM4E | |
| SCHEMBL27919270 | 0.73 | CYP2A6 (0.45) | ESRRAKDM4EMAPTTDP1CYP1A2 | |
| SCHEMBL1176869 | 0.72 | ALDH1A1 (0.45) | ESRRAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL1176865 | 0.72 | CYP2A6 (0.41) | ESRRAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL1177179 | 0.72 | MAOA (0.45) | RAB9AMEN1KMT2ANPC1KDM4E | |
| SCHEMBL11688186 | 0.70 | KMT2A (0.46) | RAB9AMEN1KMT2ANPC1KDM4E | |
| SCHEMBL1176619 | 0.69 | CYP1A2 (0.60) | RAB9AMEN1KMT2ANPC1KDM4E | |
| SCHEMBL7840769 | 0.68 | MEN1 (0.52) | MEN1KMT2AKDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110045397-A1 | CHARGE CONTROL AGENT AND RELATED ART | KURODA KAZUYOSHI | 2011-02-24 | — | — | US | disclosed |
| US-20090053641-A1 | CHARGE CONTROL AGENT AND RELATED ART | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1862860-A1 | CHARGE CONTROL AGENT AND RELATED TECHNIQUE | Orient Chemical Industries, Ltd. (JP) | 2007-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090053641-A1 | CHARGE CONTROL AGENT AND RELATED ART | H1-4, CECR2, DOT1L | ESRRA 1375/4885RAB9A 781/4885MEN1 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.