Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 11/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977029 | 0.79 | HTR1A (0.58) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL7977026 | 0.76 | HTR1A (0.58) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| Phendimetrazine SCHEMBL2325477 | 0.73 | HTR1A (0.75) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| Phendimetrazine SCHEMBL2329562 | 0.69 | HTR1A (0.59) | HTR1ADPP4SLC6A2ADRA1AHTR2B | |
| Phendimetrazine SCHEMBL160376 | 0.68 | HTR1A (0.75) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| Phendimetrazine SCHEMBL29353044 | 0.68 | HTR1A (0.75) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| Phendimetrazine SCHEMBL29554688 | 0.68 | HTR1A (0.75) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| Phendimetrazine SCHEMBL160375 | 0.68 | HTR1A (0.75) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| Phendimetrazine SCHEMBL15064941 | 0.68 | HTR1A (0.75) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 | |
| Phendimetrazine SCHEMBL10613088 | 0.67 | HTR1A (0.73) | HTR1ASLC6A2ADRA1AHTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29324-E | N-Substituted aspartyl peptide amides | G. D. SEARLE & CO. (US) | 1977-07-26 | — | — | US | disclosed |