SCHEMBL11769802

SCHEMBL11769802

C=CCc1ccc(CC=C)c(OO)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.53
ALDH1A1 P00352 4/20 0.53
PPARG P37231 2/20 0.53
PPARD Q03181 2/20 0.53
PPARA Q07869 2/20 0.53
ALOX5 P09917 5/20 0.53
CYP3A4 P08684 3/20 0.53
PTGS1 P23219 2/20 0.53
AR P10275 1/20 0.53
TRPM8 Q7Z2W7 1/20 0.53
GABRA1 P14867 8/20 0.47
GABRB2 P47870 8/20 0.47
CNR2 P34972 4/20 0.47
MAPT P10636 4/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
GAA P10253 3/20 0.47
KDM4E B2RXH2 2/20 0.47
CNR1 P21554 2/20 0.47
ALDH2 P05091 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17537909 0.81 ALDH1A1 (0.73) ALDH1A1PPARGPPARDPPARAALOX5
SCHEMBL6062868 0.80 ALDH1A1 (0.49) XDHALDH1A1PPARGPPARDPPARA
SCHEMBL1059702 0.80 ALOX5 (0.51) XDHALDH1A1PPARGPPARDPPARA
SCHEMBL8648617 0.79 ALDH1A1 (0.50) XDHALDH1A1PPARGPPARDPPARA
SCHEMBL662389 0.79 ALDH1A1 (0.80) ALDH1A1PPARGPPARDPPARAALOX5
SCHEMBL1006107 0.79 XDH (0.70) XDHALDH1A1PPARGPPARDPPARA
SCHEMBL6062233 0.77 ALDH1A1 (0.62) ALDH1A1PPARGPPARDPPARAALOX5
SCHEMBL2050350 0.76 XDH (0.54) XDHALDH1A1PPARGPPARDPPARA
SCHEMBL4451593 0.75 XDH (0.48) XDHALDH1A1PPARGPPARDPPARA
SCHEMBL1913608 0.75 ALDH1A1 (0.50) ALDH1A1GABRA1GABRB2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4001338-A PURIFICATION OF DIALKYLBENZENE DIHYDROPEROXIDE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-01-04 US claimed
US-4001338-A PURIFICATION OF DIALKYLBENZENE DIHYDROPEROXIDE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-01-04 US disclosed
US-4001338-A PURIFICATION OF DIALKYLBENZENE DIHYDROPEROXIDE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-01-04 US disclosed