SCHEMBL1059702

SCHEMBL1059702

C=CCOc1cc(CC=C)ccc1CC=C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.51
ALDH1A1 P00352 4/20 0.51
PPARA Q07869 2/20 0.51
CYP3A4 P08684 2/20 0.51
PTGS1 P23219 2/20 0.51
PPARG P37231 2/20 0.51
PPARD Q03181 2/20 0.51
AR P10275 1/20 0.51
TRPM8 Q7Z2W7 1/20 0.51
GABRA1 P14867 8/20 0.44
GABRB2 P47870 8/20 0.44
CNR2 P34972 5/20 0.44
MAPT P10636 4/20 0.44
MEN1 O00255 3/20 0.44
GAA P10253 3/20 0.44
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11586876 0.86 CNR2 (0.52) ALOX5ALDH1A1PPARACYP3A4PTGS1
SCHEMBL22701018 0.81 MAPT (0.43) ALDH1A1MAPTMEN1GAAKMT2A
SCHEMBL17537909 0.80 ALDH1A1 (0.73) ALOX5ALDH1A1PPARACYP3A4PTGS1
SCHEMBL26480555 0.80 GABRA1 (0.55) ALOX5ALDH1A1PPARACYP3A4PTGS1
SCHEMBL11769802 0.80 XDH (0.53) ALOX5ALDH1A1PPARACYP3A4PTGS1
Allyleugenol SCHEMBL2779960 0.79 ALDH1A1 (0.77) ALOX5ALDH1A1PPARACYP3A4PTGS1
Allyleugenol SCHEMBL29401211 0.79 ALDH1A1 (0.77) ALOX5ALDH1A1PPARACYP3A4PTGS1
SCHEMBL2846385 0.79 ALDH1A1 (0.77) ALOX5ALDH1A1PPARACYP3A4PTGS1
SCHEMBL22215811 0.78 LMNA (0.61) ALOX5ALDH1A1PPARACYP3A4PTGS1
SCHEMBL2842624 0.78 FLT3 (0.51) ALOX5ALDH1A1PPARACYP3A4PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699310-B Curable resin composition, fuel cell, and sealing method 三键有限公司 2024-02-20 CN disclosed
US-11834554-B2 Conductive silicone composition and cured product thereof THREEBOND CO., LTD. (JP) 2023-12-05 US disclosed
CN-113045706-B Low-adhesion photo-curable resin composition and high-speed three-dimensional printing method 台科三维科技股份有限公司 2023-09-08 CN disclosed
WO-2023119819-A1 CURABLE RESIN COMPOSITION 株式会社スリーボンド 2023-06-29 WO disclosed
CN-116195039-A Thin film transistor element and method for manufacturing the same 株式会社钟化 2023-05-30 CN disclosed
US-20230155034-A1 THIN-FILM TRANSISTOR ELEMENT AND METHOD FOR MANUFACTURING THE SAME KANEKA CORPORATION (JP) 2023-05-18 US disclosed
EP-3611227-B1 CURABLE RESIN COMPOSITION, FUEL CELL USING SAME, AND SEALING METHOD THREE BOND CO LTD (JP) 2022-12-21 EP disclosed
CN-109791358-B Photosensitive composition, colored pattern and method for producing the same 株式会社钟化 2022-09-02 CN disclosed
EP-4023716-A1 TWO-COMPONENT-TYPE RESIN COMPOSITION FOR HEAT-RADIATING MATERIAL Nippon Shokubai Co., Ltd. (JP) 2022-07-06 EP disclosed
CN-109476925-B Curable resin composition, cured product, fuel cell, and sealing method 三键有限公司 2022-02-22 CN disclosed
US-8273842-B2 Process for production of cyclic polyorganosiloxane, curing agent, curable composition, and cured product of the curable composition KANEKA CORPORATION (JP) 2012-09-25 US disclosed
US-8263725-B2 Curable composition KANEKA CORPORATION (JP) 2012-09-11 US disclosed
US-20110237702-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT KANEKA CORPORATION (JP) 2011-09-29 US disclosed
EP-2343326-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT Kaneka Corporation (JP) 2011-07-13 EP disclosed
US-20110001190-A1 ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR KANEKA CORPORATION (JP) 2011-01-06 US disclosed
US-20100267919-A1 PROCESS FOR PRODUCTION OF CYCLIC POLYORGANOSILOXANE, CURING AGENT, CURABLE COMPOSITION, AND CURED PRODUCT OF THE CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-10-21 US disclosed
EP-2236543-A1 ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR Kaneka Corporation (JP) 2010-10-06 EP disclosed
US-20100222525-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-09-02 US disclosed
EP-2216336-A1 PROCESS FOR PRODUCTION OF CYCLIC POLYORGANOSILOXANE, CURING AGENT, CURABLE COMPOSITION, AND CURED PRODUCT OF THE CURABLE COMPOSITION Kaneka Corporation (JP) 2010-08-11 EP disclosed
EP-1967540-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-09-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110001190-A1 ALKALI-DEVELOPABLE CURABLE COMPOSITION, INSULATING THIN FILM USING THE SAME, AND THIN FILM TRANSISTOR TET1, KDM4A, ASIC1 ALOX5 1349/4885ALDH1A1 638/4885PPARA 4708/4885
US-20100267919-A1 PROCESS FOR PRODUCTION OF CYCLIC POLYORGANOSILOXANE, CURING AGENT, CURABLE COMPOSITION, AND CURED PRODUCT OF THE CURABLE COMPOSITION SMCHD1, SQLE, SMARCA5 ALOX5 88/4885ALDH1A1 1525/4885PPARA 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.