Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062868 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL17537909 | 0.84 | ALDH1A1 (0.73) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| Estragole SCHEMBL28095175 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| Estragole SCHEMBL900647 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| Estragole SCHEMBL57204 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL2845262 | 0.77 | APLNR (0.58) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL11769802 | 0.77 | XDH (0.53) | ALDH1A1CYP3A4SMN1; SMN2PPARAPPARG | |
| SCHEMBL30105464 | 0.77 | APLNR (0.58) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| Estragole SCHEMBL29106756 | 0.77 | ALDH1A1 (0.69) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL2096402 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105577-B2 | for finishing of undyed and dyed or printed fibre materials; treatment of skin, mucous membrane or hair, hard surfaces, oral care; detergent | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |
| US-20040186174-A1 | Hydroxydiphenyl ether compounds | HOLZL WERNER (FR) | 2004-09-23 | — | — | US | disclosed |
| US-20030162836-A1 | Hydroxydiphenyl ether compounds | HOLZL WERNER (FR) | 2003-08-28 | — | — | US | disclosed |
| EP-1053989-A2 | Hydroxydiphenyl ether compounds | Ciba SC Holding AG (CH) | 2000-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186174-A1 | Hydroxydiphenyl ether compounds | HPD, DDT, HAAO | ALDH1A1 1109/4885CYP3A4 5/4885SMN1; SMN2 4792/4885 |
| US-20030162836-A1 | Hydroxydiphenyl ether compounds | HPD, DDT, HAAO | ALDH1A1 1109/4885CYP3A4 5/4885SMN1; SMN2 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.